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Category:
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7TM Receptors Leukotriene Receptors
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Cat.No.
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Product Name
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2025 |
Cinalukast
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| Alternative name(s): |
Ro 24-5913 |
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Price and Availability
Click here for full price details of
Cinalukast
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Chemical Name:
4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]
amino]-2,2-diethyl-4-oxobutanoic acid |
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Biological Activity:
Potent, selective CysLT1 (LTD4)
leukotriene receptor antagonist (IC50 = 6.4 nM). Inhibits LTD4-induced
bronchoconstriction in guinea pigs when administered intravenously, orally or
by aerosol.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
O'Donnell
(1991) Ro 24-5913: a
potent, specific, orally active LTD4 antagonist. Ann.N.Y.Acad.Sci. 629
413. O'Donnell et al (1991) Pharmacologic actions of Ro 24-5913,
a novel antagonist of leukotriene D4. J.Pharmacol.Exp.Ther. 259
751.
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or by Research Area
Keywords: Cinalukast, Leukotriene Receptors, Potent, Selective CysLT1 (LTD4) Antagonist; Orally Active, Ro 24-5913, Tocris Bioscience
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