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Category:
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7TM Receptors Dopamine ReceptorsD2-like ReceptorsAntagonists
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Cat.No.
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Product Name
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0782 |
2-Chloro-11-(4-methylpiperazino)dibenz[b,f]oxepin maleate
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Price and Availability
Click here for full price details of
2-Chloro-11-(4-methylpiperazino)dibenz[b,f]oxepin maleate
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Biological Activity:
Dopamine D2-like receptor
antagonist that displays some selectivity for D4 receptors (Ki
values are 0.54 and 2.5 nM for D4 and D2 receptors
respectively).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Phillips et al (1994) Binding of
5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptane analogues
of clozapine to dopamine and serotonin receptors. J.Med.Chem. 37
2686. Phillips et al (1995) Binding of
5H-dibenzo[a,d]cycloheptane and dibenz[b,f]oxapin analogues of clozapine to
dopamine and serotonin receptors. J.Med.Chem. 38 708. Zawilska
et al (2003) L-745,870 suppresses the nighttime serotonin
N-acetyltransferase activity in chick retina: in vivo evidence for agonist
activity at D4-dopamine receptors. J.Neural Transm. 110
219.
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View related products by Pharmacological Action
or by Research Area
Keywords: 2-Chloro-11-(4-methylpiperazino)dibenz[b,f]oxepin Maleate, Dopamine Receptors, D2-like Antagonist. Displays Some D4 Selectivity, 2Chloro-11-(4-methylpiperazino)dibenz[b,f]oxepin Maleate, Tocris Bioscience
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