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Category: EnzymesarrowPhosphatasesarrowPP
Cat.No. Product Name
0744 Ceramide  
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Ceramide
Chemical Name: N-Acetylsphingosine

Biological Activity:

A potent modulator of cell proliferation and differentiation.

Technical Data:

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M.Wt: 341.53
Formula: C20H39NO3
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Ethanol and to 100 mM in DMSO
CAS No: [3102-57-6]

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    References:

    Kim et al (1991) Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-interferon. J.Biol.Chem. 266 484. Dobowsky and Hannun (1992) Ceramide stimulates a cytosolic protein phosphatase. J.Biol.Chem. 267 5048. Quintans et al (1994) Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochem.Biophys.Res.Comm. 202 710. Xie and Johnson (1997) Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. J.Neurochem. 69 1020.
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    Keywords: Ceramide , Phosphatases, Ser / Thr Protein Phosphatase Activator, Tocris Bioscience
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