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Keywords: (S)-4-Carboxyphenylglycine, Glutamate (Metabotropic) Receptors, Competitive Group I MGlu Antagonist / Weak Group II Agonist, 4Carboxyphenylglycine, Tocris Bioscience
Displays 26-fold and > 440-fold selectivity over kainate and NMDA receptors respectively. Neuro-protective; delays neuronal death in a global ischaemia model and cerebral infarction in a focal ischaemia model.
