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Category:
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Enzymes PhosphatasesPP
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Cat.No.
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Product Name
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1891 |
Calcineurin Autoinhibitory Peptide
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| Alternative name(s): |
Autoinhibitory
peptide 457-482 |
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Price and Availability
Click here for full price details of
Calcineurin autoinhibitory peptide
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Biological Activity:
Selective
inhibitor of Ca2+-calmodulin-dependent protein phosphatase
(calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM
kinase II (IC50 > 100 μM).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Hashimoto et al (1990) Identification
of an autoinhibitory domain in calcineurin. J.Biol.Chem. 265
1924. Yokoyama and Wang (1994) The role of the autoinhibitory domain in
differential metal ion activation of calmodulin-stimulated phosphatase. FEBS
Lett. 337 128. Perrino et al (1995) Calcium
regulation of calcineurin phosphatase activity by its B subunit and calmodulin.
J.Biol.Chem. 270 340.
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Keywords: Calcineurin Autoinhibitory Peptide, Phosphatases, Selective Calcineurin Inhibitor, Autoinhibitory Peptide 457-482, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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