CGP 53353 | Kinases | Selective Inhibitor Of PKCbII | CGP53353

Category:

Cat.No.	Product Name
2442	CGP 53353

Price and Availability

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CGP 53353

Chemical Name: 5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dio ne

Biological Activity:

Selective inhibitor of PKCβII (IC₅₀ values are 0.41 and 3.8 μM for PKCβII and PKCβI respectively).

Technical Data:

M.Wt:	365.34
Formula:	C₂₀H₁₃F₂N₃O₂
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO and to 20 mM in Ethanol
Purity:	>99%
CAS No:	[145915-60-2]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Kouroedov et al (2004) Selective inhibition of protein kinase Cβ₂ prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 110 91.

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Keywords: CGP 53353, Kinases, Selective Inhibitor Of PKCbII, CGP53353, Tocris Bioscience

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