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Category: EnzymesarrowSynthases/SynthetasesarrowNO SynthasesarrownNOS
Cat.No. Product Name
0735 3-Bromo-7-nitroindazole  
Price and Availability

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3-Bromo-7-nitroindazole

Biological Activity:

An even more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole (0602).

Technical Data:

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M.Wt: 242.03
Formula: C7H4BrN3O2
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in DMSO and to 50 mM in Ethanol
Purity: >98%
CAS No: [74209-34-0]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch
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    References:

    Bland-Ward et al (1994) Isoform selectivity of indazole-based nitric oxide synthase inhibitors. Br.J.Pharmacol. 112 351P. Bland-Ward and Moore (1995) 7-Nitroindazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci. 57 PL131.
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    Keywords: 3-Bromo-7-nitroindazole, Synthases / Synthetases, Selective NNOS Inhibitor, 3Bromo-7-nitroindazole, Tocris Bioscience

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    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
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    Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..”
    Researcher, University of Aberdeen, UK
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