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Category: EnzymesarrowOxygenases/OxidasesarrowMonoamine Oxidase
Cat.No. Product Name
0767

Bifemelane hydrochloride  

Price and Availability

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Bifemelane
Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride

Biological Activity:

Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

Technical Data:

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M.Wt: 305.84
Formula: C18H23NO.HCl
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in Water and to 100 mM in DMSO
Purity: >99%
CAS No: [90293-01-9]

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    References:

    Tobe et al (1981) Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneim.-Forsch. 31 1278. Naoi et al (1988) 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 50 243. Nomoto et al (1994) Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 178 95.
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    Keywords: Bifemelane, Oxygenases / Oxidases, MAO-A & MAO-B Inhibitor, Tocris Bioscience
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