Click here for full price details of (-)-Bicuculline methochloride
Chemical Name:[R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodi
oxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[
4,5-g]isoquinolinium chloride
Biological Activity:
Methochloride salt of
(+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA
receptor-mediated actions reported.
Kempet al (1986) Quantitative evaluation of the potencies of
GABA-receptor agonists and antagonists using the rat hippocampal slice
preparation. Br.J.Pharmacol. 87 677. Seutin and Johnson
(1999) Recent advances in the pharmacology of quaternary salts of bicuculline.
TiPS 20 268.
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