(RS)-Baclofen | GABAB Receptors | Selective GABAB Agonist | Baclofen

Category:

Cat.No.	Product Name
0417	(RS)-Baclofen

Price and Availability

Click here for full price details of
(RS)-Baclofen

Chemical Name: (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid

Biological Activity:

Selective GABA_B receptor agonist. Skeletal muscle relaxant.

Technical Data:

M.Wt:	213.66
Formula:	C₁₀H₁₂CINO₂
Storage:	Store at RT
Solubility:	Soluble to 100 mM in 1eq. NaOH
Purity:	>99%
CAS No:	[1134-47-0]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Hill et al (1981) ³H-Baclofen and ³H-GABA bind to bicuculline-insensitive GABA_B sites in rat brain. Nature 290 149. Berthelot et al (1991) 3-Thienylaminobutyric acid and 3-furylaminobutyric acids - synthesis and GABA_B receptor binding studies. J.Med.Chem. 34 2557. Bowery et al (1993) GABA_B receptor pharmacology. Ann.Rev.Pharmacol.Toxicol. 33 109.

View related products by Pharmacological Action or by Research Area

Keywords: (RS)-Baclofen, GABAB Receptors, Selective GABAB Agonist, Baclofen, Tocris Bioscience

Literature in this Area

Scientific Reviews

GABA Receptors
Download PDF

Featured New Product

Antagonist of neurosteroid potentiation of GABA_A

2681 17-PA

Selective antagonist of neuro-steroid potentiation and direct gating of GABA_A receptors. Selectively reduces the effects of 5α-reduced steroids compared to 5β-reduced steroids & displays no effect on potentiation evoked by barbiturates & benzodiazepines. Attenuates 3α,5α-THP-induced loss of righting reflex and total sleep time following i.c.v administration in rats.

View all Featured New Products

New Products in this Area

Check back soon!
We are currently working on new products for this area

User ID
Password