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Category: 7TM Receptorsarrow5-HT Receptorsarrow5-HT2 Receptorsarrow5-HT2B
Cat.No. Product Name
1059

BW 723C86 hydrochloride

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BW 723C86 hydrochloride
Chemical Name: a-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride

Biological Activity:

Selective 5-HT2B receptor agonist.

Technical Data:

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M.Wt: 322.85
Formula: C16H18N2OS.HCl
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in DMSO
Purity: >99%
CAS No: [160521-72-2]

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    References:

    Kennett et al (1996) Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety. Br.J.Pharmacol. 117 1443. Kennett et al (1997) BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats. Neuropharmacology 36 233. Duxon et al (1997) Activation of 5-HT2B receptors in the medial amygdala causes anxiolysis in the social interaction test in the rat. Neuropharmacology 36 601. Kennett et al (1998) Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated. Neuropharmacology 37 1603.
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    Keywords: BW 723C86 Hydrochloride, 5-HT Receptors, 5-HT2B Agonist, BW723C86 Hydrochloride, Tocris Bioscience
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