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Category:
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Enzymes ATPases/GTPasesATPase
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Cat.No.
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Product Name
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1870 |
BTS
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Price and Availability
Click here for full price details of
BTS
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Chemical Name:
4-Methyl-N-(phenylmethyl)benzenesulfonamide |
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Biological Activity:
Selective
inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1
(S1) (IC50 ~ 5 μM). Reversibly blocks gliding
motility and suppresses force and twitch production in fast skeletal muscle.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Cheung et al (2001) A small-molecule
inhibitor of skeletal muscle myosin II. Nature Cell Biol. 4 83. Ramachandran
et al (2003) Skeletal muscle myosin cross-bridge cycling is necessary
for myofibrillogenesis. Cell Motil.Cytoskeleton 55 61. Shaw
et al (2003) Mechanism of inhibition of skeletal muscle actomyosin by
N-benzyl-p-toluenesulfonamide. Biochemistry 42 6128.
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View related products by Pharmacological Action
or by Research Area
Keywords: BTS, ATPases / GTPases, Selective Inhibitor Of Skeletal Muscle Myosin II ATPase Activity, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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