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Category: Cellular Processes and ComponentsarrowSignal TransductionarrowCalcium SignallingarrowCalcium ATPase Modulators
Cat.No. Product Name
1236 BHQ
Price and Availability

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BHQ
Chemical Name: 1,4-Dihydroxy-2,5-di-tert-butylbenzene

Biological Activity:

A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.

Technical Data:

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M.Wt: 222.33
Formula: C14H22O2
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO
CAS No: [88-58-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Hassessian et al (1994) Blockade of the inward rectifier potassium current by the Ca2+-ATPase inhibitor 2¢,5¢-di(tert-butyl)-1,4-benzohydroquinone (BHQ). Br.J.Pharmacol. 112 1118. Jan et al (1999) Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced Ca2+ signals in Madin Darby canine kidney cells. Eur.J.Pharmacol. 365 111. Fusi et al (1999) 2,5-Di-t-butyl-1,4 benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta. Eur.J.Pharmacol. 366 181. Dettbarn and Palade (1999) Effects of three sarcoplasmic/endoplasmic Ca++ pump inhibitors on release channels and intracellular stores. J.Pharmacol.Exp.Ther. 285 729.
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    Keywords: BHQ, Signal Transduction, Inhibitor Of SERCA ATPase, Tocris Bioscience

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