Tocris Bioscience
 Welcome to Tocris

Home Products Technical Support Customer Support Literature Custom Synthesis
Category: Other ActivitiesarrowSigma and ImidazolinearrowSigma LigandsarrowGeneral Sigma
Cat.No. Product Name
0511 BD 1008 dihydrobromide
Price and Availability

Click here for full price details of
BD 1008 dihydrobromide
Chemical Name: N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidi nyl)ethylamine dihydrobromide

Biological Activity:

Potent and selective σ-ligand; Ki against [3H]-(+)-3-PPP = 0.34 nM.

Technical Data:

 Click here for more information on batch specific data
M.Wt: 463.08
Formula: C15H22Cl2N2.2HBr
Storage: Desiccate at -20°C
Solubility: Soluble to 50 mM in Water
CAS No: [138356-08-8]

Resources:

    		•

    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    De Costa et al (1992) Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines - structural requirements and binding affinity at the sigma receptor. J.Med.Chem. 35 38. Monnet et al (1996) Differentiation of σ ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices. Br.J.Pharmacol. 119 65. Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326.
    View related products by Pharmacological Action or by Research Area

    Keywords: BD 1008 Dihydrobromide, Sigma & Imidazoline, Potent, Selective S Ligand, BD1008 Dihydrobromide, Tocris Bioscience
    New Product Guide
    Tocris Bioscience. Our latest New Product Guide highlights over 140 new productsOur latest New Product Guide highlights over 140 new products.
    Request Copy / View PDF
    Unique & Diverse Compound Libraries
    Tocriscreen Collections : For pricing and compound information click here
    Fully annotated small molecule libraries for HTS, HCS and
    chemical biology applications.
    • 1120 compounds
    • Pre-dissolved in DMSO
    Tocriscreen Total (250 μL/well)
    Tocriscreen Mini (50 μL/well)
    New Products in this Area

     2669TC 1
     High affinity σ1 ligand
     2562PB 28 dihydrochloride
     High affinity σ2 agonist
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account
    Home | About | Contact | Environment | Distributors | Glossary | Ordering | Security | Privacy | Terms & Conditions | Services | Site Map