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Category: Enzyme-Linked ReceptorsarrowReceptor Tyrosine Kinases (RTKs)arrowTRK
Cat.No. Product Name
2837 BDNF (human)
Price and Availability

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BDNF (human)

Other Information:

Recombinant protein, expressed in Escherichia coli

Biological Activity:

Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorder such as Parkinson's and Alzheimer's disease.

Technical Data:

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M.Wt: 26984
Storage: Store at -20°C
Solubility: Soluble in Water
CAS No: [218441-99-7]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch Product/Material Safety Data Sheet: View current batch

    References:

    Evans and Barker (2008) Neurotrophic factors as a therapeutic target for Parkinson's disease. Expert Opin.Ther.Targets 12 437. Wang et al (2008) The when and where of BDNF and the antidepressant response. Biol.Psychiat. 63 640. Lipsky and Marini (2007) Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. 1122 130.
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    Keywords: BDNF (human), Receptor Tyrosine Kinases (RTKs), Activates TrkB & P75 Receptors, Tocris Bioscience

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