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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowAMPA / Kainate SelectivearrowDesensitization Modulators
Cat.No. Product Name
1048 1-BCP
Price and Availability

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1-BCP
Chemical Name: 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine

Biological Activity:

A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.

Technical Data:

 Click here for more information on batch specific data
M.Wt: 233.27
Formula: C13H15NO3
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO
CAS No: [34023-62-6]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Arai et al (1994) A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 638 343. Desai et al (1995) 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices. Neuropharmacology 34 141. Vanover (1997) Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion. Eur.J.Pharmacol. 332 115. Yamada et al (1998) AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons. Neurosci.Lett. 249 119.
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    Keywords: 1-BCP, Ligand-gated Ion Channels, Modulates AMPA-mediated Responses, 1BCP, Tocris Bioscience
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