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Category:
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Cellular Processes and Components Cell MetabolismLipid Metabolism
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Cat.No.
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Product Name
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2756 |
Arachidonic acid (in TocrisolveTM 100)
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Price and Availability
Click here for full price details of
Arachidonic acid (in Tocrisolve 100)
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Chemical Name:
5Z,8Z,11Z,14Z-Eicosatetraenoic acid |
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Biological Activity:
Endogenous free fatty acid released from
phospholipids by phospholipase A2. Important cellular signalling
mediator and precursor of eicosanoids. Metabolised by lipoxygenases,
cyclooxygenases and cytochrome P450 monooxygenases.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Nakanishi et al
(2006) Roles of cPLA2α
and arachidonic acid in cancer. Biochim.Biophys.Acta 1761 1335. Levick
et al (2007) Arachidonic acid metabolism as a potential mediator of
cardiac fibrosis associated with inflammation. J.Immunol. 178
641. Higuchi et al (2007) Arachidonic acid promotes
glutamate-induced cell death associated with necrosis by 12-lipoxygenase
activation in glioma cells. Life Sci. 80 1856.
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View related products by Pharmacological Action
or by Research Area
Keywords: Arachidonic Acid (in Tocrisolve 100), Cell Metabolism, Endogenous Free Fatty Acid (in Water-soluble Emulsion), Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..” Researcher, University of Aberdeen, UK |
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