Anpirtoline Hydrochloride | 5-HT Receptors | Highly Potent 5-HT1B Agonist. Also 5-HT3 Antagonist

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Cat.No.	Product Name
0703	Anpirtoline hydrochloride

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Anpirtoline hydrochloride

Chemical Name: 6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride

Biological Activity:

Highly potent 5-HT_1B receptor agonist.

Technical Data:

M.Wt:	265.2
Formula:	C₁₀H₁₃CIN₂S.HCl
Storage:	Desiccate at +4°C
Solubility:	Soluble to 100 mM in Water
CAS No:	[98330-05-3]

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References:

Schlicker et al (1992) Anpirtoline, a novel, highly potent 5-HT_1B receptor agonist with antinociceptive/antidepressant-like actions in rodents. Br.J.Pharmacol. 105 732. Swedberg et al (1992) D-16949 (anpirtoline): a novel serotonergic (5-HT_1B) psychotherapeutic agent assessed by its discriminative effect in the rat. J.Pharmacol.Exp.Ther. 263 1015. Göthert et al (1995) 5HT₃ receptor antagonism by anpirtoline, a mixed 5HT₁ receptor agonist/5HT₃ receptor antagonist. Br.J.Pharmacol. 114 269.

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Keywords: Anpirtoline Hydrochloride, 5-HT Receptors, Highly Potent 5-HT1B Agonist. Also 5-HT3 Antagonist, Tocris Bioscience

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