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Category: Cellular Processes and ComponentsarrowCell MetabolismarrowAmyloid Beta Peptides
Cat.No. Product Name
1894 Amyloid b-Peptide (12-28) (human)
Price and Availability

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Amyloid beta-peptide (12-28) (human)

Biological Activity:

Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.

Technical Data:

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M.Wt: 1955.2
Formula: C89H135N25O25
Storage: Desiccate at -20°C
CAS No: [107015-83-8]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Flood et al (1994) An amyloid β-protein fragment, A β[12-28], equipotent impairs post-training memory processing when injected into different limbic system structures. Brain Res. 663 271. Ray et al (1998) Binding of amyloid β-protein to intracellular brain proteins in rat and human. Neurochem.Res. 23 1277. Freir and Herron (2003) Nicotine enhances the depressive actions of A β 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo. J.Neurophysiol. 89 2917.
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    Keywords: Amyloid Beta-peptide (12-28) (human), Cell Metabolism, Amyloid B-peptide; Minimum Required For Binding To Brain Proteins, Tocris Bioscience

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    Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..”
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