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Category: 7TM ReceptorsarrowHistamine ReceptorsarrowH2 ReceptorsarrowAgonists
Cat.No. Product Name
0668 Amthamine dihydrobromide  
Price and Availability

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Amthamine dihydrobromide
Chemical Name: 2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide

Biological Activity:

Highly selective H2 agonist, slightly more potent than histamine itself. Only a weak antagonist at H3 and has no activity at H1 receptors.

Technical Data:

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M.Wt: 319.06
Formula: C6H11N3S.2HBr
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Water
CAS No: [142437-67-0]

Resources:

  • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Eriks et al (1992) Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazole. J.Med.Chem. 35 3239. Poli et al (1993) In vitro cardiac pharmacology of the new histamine H2 receptor agonist amthamine; comparisons with histamine and dimaprit. Agents Actions 40 44. Coruzzi et al (1993) The new potent and selective histamine H2 receptor agonist amthamine as a tool to study gastric secretion. Naunyn-Schmied.Arch.Pharmacol. 348 77.
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    Keywords: Amthamine Dihydrobromide, Histamine Receptors, Highly Selective Standard H2 Agonist, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Histamine Receptors
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