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Category: EnzymesarrowPolymerasesarrowPoly(ADP-ribose) Polymerase
Cat.No. Product Name
0788 3-Aminobenzamide  
Alternative name(s): 3-ABA
Price and Availability

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3-Aminobenzamide

Biological Activity:

An inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.

Technical Data:

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M.Wt: 136.15
Formula: C7H8N2O
Storage: Store at RT
Solubility: Soluble to 100 mM in Water
CAS No: [3544-24-9]

Resources:

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    References:

    Malorni et al (1995) 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem.Biophys.Res.Comm. 207 715. Cuzzocrea et al (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br.J.Pharmacol. 121 1065.
    View related products by Pharmacological Action or by Research Area

    Keywords: 3-Aminobenzamide, Polymerases, PARP Inhibitor, 3-ABA, 3Aminobenzamide, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
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