3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile Maleate | Ligand-gated Ion Channels | 5-HT3 Antagonist

Welcome to Tocris

View Basket | Checkout | Log In

Target Detective

Category:

Ion Channels

Ligand-gated Ion Channels

5-HT3 Receptors

Antagonists

Cat.No.	Product Name
0666	3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate

Price and Availability:

For 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate pricing & availability please select your country from the drop down menu :

Please select your country for pricing & availability of 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate

Biological Activity:

A competitive 5-HT₃ antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.

Technical Data:

M.Wt:	395.42
Formula:	C₁₆H₁₇N₅.C₄H₄O₄
Solubility:	Soluble to 100 mM in DMSO
Storage:	Desiccate at -20°C

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service

Product/Material Safety Data Sheet: View current batch

References:

Monge et al (1993) Novel antagonists of 5-HT₃ receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J.Med.Chem. 36 2745.

View related products by Pharmacological Action or by Research Area

Keywords: 3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile Maleate, Ligand-gated Ion Channels, 5-HT3 Antagonist, Tocris Bioscience

Literature in this Area

Scientific Reviews

5-HT Receptors & their Ligands
Download PDF

Signal Transduction Guide

	A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
View PDF

Endocrinology Guide

Highlights over 200 products

Request copy | View PDF

New Products in this Area

	2728	ACET
	Potent antagonist of GluR5-containing kainate receptors
	3110	(-)-Cotinine
	Major metabolite of nicotine
	2995	NS 1738
	Positive allosteric modulator of a7 nAChR; active in vivo
	3124	a-Conotoxin EI
	a1b1dg selective nAChR antagonist
	3121	a-Conotoxin PIA
	Selective antagonist of a6-containing nicotinic receptors
	3048	Valerenic acid
	Positive allosteric modulator of GABA_A receptors
	3119	a-Conotoxin ImI
	a7 and a9 selective nAChR antagonist
	2557	Phencyclidine hydrochloride
	Non-competitive NMDA receptor antagonist
	3087	Lorazepam
	Acts at the benzodiazepine modulatory site
	2733	U 90042
	GABA_A receptor ligand
	1340	a-Conotoxin MII
	Potent a3b2 and b3 subunit selective nicotinic antagonist
	3046	Alphaxalone
	Direct activator and potentiator of GABA_A
	2980	CX 546
	AMPA receptor potentiator
	3071	Dextromethorphan hydrobromide
	NMDA receptor antagonist
	3083	DMCM hydrochloride
	Benzodiazepine inverse agonist
	2905	TB 21007
	a5-selective GABA_A inverse agonist
	2738	Org 20599
	Positive allosteric modulator and direct agonist of GABA_A receptors
	2805	Diazepam
	Acts at the benzodiazepine modulatory site
	2832	Midazolam hydrochloride
	Benzodiazepine agonist
	2972	A 438079 hydrochloride
	Competitve P2X₇ antagonist
	2736	Sazetidine A dihydrochloride
	Subtype-selective a4b2 receptor desensitiser
	2929	PEPA
	Allosteric potentiator of AMPA receptor desensitisation
	2973	Piracetam
	Nootropic; modulates Na⁺-flux at AMPA receptors
	2734	U 89843A
	Positive allosteric modulator of GABA_A
	2903	Granisetron hydrochloride
	5-HT₃ antagonist
	2782	TCS 46b
	Orally active, subtype-selective NR1A/NR2B antagonist
	2931	Spinorphin
	Potent P2X₃ antagonist
	2851	Nefiracetam
	Cognitive enhancer
	2770	Philanthotoxin 74
	GluR1/2 selective AMPA antagonist
	2891	Ondansetron hydrochloride
	Selective 5-HT₃ antagonist
	2820	(+)-Tubocurarine chloride
	Nicotinic receptor antagonist
	2843	Mecamylamine hydrochloride
	Non-competitive nicotinic receptor antagonist
	2810	Carbamoylcholine chloride
	Cholinergic receptor agonist
	1521	LY 233053
	Competitive NMDA receptor antagonist
	2745	U 93631
	GABA_A receptor antagonist
	2785	Strychnine hydrochloride
	Competitive glycine receptor antagonist
	2737	TC 2559 difumarate
	Selective partial agonist at a4b2 receptors
	2809	Acetylcholine chloride
	Endogenous neurotransmitter
	2681	17-PA
	Antagonist of neurosteroid potentiation and direct gating of GABA_A

for new product e-alerts

User ID
Password