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Category: Cellular Processes and ComponentsarrowCell MetabolismarrowLipid Metabolism
Cat.No. Product Name
2784 Acipimox
Price and Availability

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Acipimox
Chemical Name: 5-Methyl-4-oxide-2-pyrazinecarboxylic acid

Biological Activity:

Antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.

Technical Data:

Click here for more information on batch specific data
M.Wt: 154.12
Formula: C6H6N2O3
Storage: Store at RT
Solubility: Soluble to 100 mM in Water and to 100 mM in DMSO
Purity: >99%
CAS No: [51037-30-0]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Lovisolo et al (1981) Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy. Pharmacol.Res.Comms. 13 163. Christie et al (1996) Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetol. 39 45. Wang-Fisher et al (2002) Acipimox stimulates leptin production from isolated rat adipocytes. J.Endocrinol. 174 267.
    View related products by Pharmacological Action or by Research Area

    Keywords: Acipimox, Cell Metabolism, Antilipolytic Agent, Tocris Bioscience

    Literature in this Area
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    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    Purity To Rely On
    When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.

    Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.

    This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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