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Category:
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Cellular Processes and Components Extracellular Matrix and Adhesion MoleculesAdhesion Molecules
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Cat.No.
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Product Name
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1845 |
Ac2-26
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Price and Availability
Click here for full price details of
Ac2-26
Other Information:
Sold under licence from The William Harvey Research
Institute
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Biological Activity:
Annexin/lipocortin
1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil
adhesion and emigration, and promotes detachment of neutrophils from activated
mesenteric endothelium in mice in vivo. Anti-inflammatory.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Perretti et al (1993) Lipocortin-1
fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the
mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.
J.Immunol. 151 4306. Lim et al (1998) Promoting
detachment of neutrophils adherent to murine postcapillary venules to control
inflammation: effect of lipocortin 1. Proc.Natl.Acad.Sci.USA 95
14535. Perretti and Gavins (2003) Annexin 1: an endogenous
anti-inflammatory protein. News Physiol.Sci. 18 60.
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View related products by Pharmacological Action
or by Research Area
Keywords: Ac2-26, Extracellular Matrix & Adhesion Molecules, Annexin / Lipocortin 1-mimetic; Inhibits Leukocyte Extravasation, Ac226, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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