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Category:
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Cellular Processes and Components Extracellular Matrix and Adhesion MoleculesAdhesion Molecules
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Cat.No.
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Product Name
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1846 |
Ac2-12
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Price and Availability
Click here for full price details of
Ac2-12
Other Information:
Sold under licence from The William Harvey Research
Institute
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Biological Activity:
Annexin/lipocortin
1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil
adhesion and emigration, and promotes detachment of neutrophils from activated
mesenteric endothelium in mice in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Lim et al (1998) Promoting
detachment of neutrophils adherent to murine postcapillary venules to control
inflammation: effect of lipocortin 1. Proc.Natl.Acad.Sci.USA 95
14535. Perretti et al (2001) Involvement of the receptor for
formylated peptides in the in vivo anti-migratory actions of annexin 1
and its mimetics. Am.J.Pathol. 158 1969.
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View related products by Pharmacological Action
or by Research Area
Keywords: Ac2-12, Extracellular Matrix & Adhesion Molecules, Annexin / Lipocortin 1-mimetic; Inhibits Leukocyte Extravasation, Ac212, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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