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Category:
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Enzymes CyclaseGuanylyl Cyclase
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Cat.No.
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Product Name
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2753 |
A 350619 hydrochloride
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Price and Availability
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A 350619 hydrochloride
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Chemical Name:
3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)b
utyl]-2-propenamide hydrochloride |
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Biological Activity:
Activator of soluble guanylyl cyclase (sGC).
Activates basal sGC and synergistically activates sGC in the presence of NO.
Relaxes cavernosum smooth muscle in vitro and induces penile erections in rats
in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Miller et al
(2003) A-350619: a novel activator of soluble guanylyl cyclase. Life Sci. 72
1015. Evgenov et al (2006) NO-independent stimulators and
activators of soluble guanylate cyclase: discovery and therapeutic potential.
Nat.Rev.Drug Discov. 5 755.
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or by Research Area
Keywords: A 350619 Hydrochloride, Cyclase, Soluble Guanylyl Cyclase (sGC) Activator, A350619 Hydrochloride, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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