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Category: Cellular Processes and ComponentsarrowSignal TransductionarrowCytokine and NFkB SignallingarrowCytokines
Cat.No. Product Name
2446 AS 101
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AS 101
Chemical Name: Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate

Biological Activity:

Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNFα release.

Technical Data:

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M.Wt: 312.05
Formula: C2H4Cl3O2Te.NH4
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in DMSO and to 10 mM in Ethanol
CAS No: [106566-58-9]

Resources:

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    References:

    Kalechman et al (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis. J.Biol.Chem. 279 24724.
    View related products by Pharmacological Action or by Research Area

    Keywords: AS 101, Signal Transduction, Immunomodulator; Inhibits IL-10 Synthesis & Potentiates IL-1a, IL-2 & TNFa Release, AS101, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
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