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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAntagonists
Cat.No. Product Name
0105 DL-AP5  
Alternative name(s): DL-APV
DL-2-Amino-5-phosphonovaleric acid
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DL-AP5
Chemical Name: DL-2-Amino-5-phosphonopentanoic acid

Biological Activity:

Potent NMDA antagonist. See separate isomers 0106 and 0107.

Technical Data:

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M.Wt: 197.13
Formula: C5H12NO5P
Storage: Store at RT
Solubility: Soluble to 10 mM in Water and to 100 mM in 1eq. NaOH
Purity: >99%
CAS No: [76326-31-3]

Resources:

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    References:

    Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378.

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    Keywords: DL-AP5, Ligand-gated Ion Channels, Potent, Selective NMDA Antagonist, DL-APV, DL-2-Amino-5-phosphonovaleric Acid, DLAP5, Tocris Bioscience
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