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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAgonists
Cat.No. Product Name
0186 cis-ACPD  
Price and Availability

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cis-ACPD
Chemical Name: (±)-1-Aminocyclopentane-cis-1,3-dicarboxylic acid

Biological Activity:

1:1 mixture of (1R,3R)- and (1S,3S)-ACPD. Potent NMDA receptor agonist.

Technical Data:

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M.Wt: 173.17
Formula: C7H11NO4
Storage: Store at RT
Solubility: Soluble to 100 mM in 1eq. NaOH

Resources:

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    • Certificate of Analysis / MSDS:

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    References:

    McLennan (1983) Receptors for the excitatory amino acids in the mammalian central nervous system. Progr.Neurobiol. 20 251. Olverman et al (1988) Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17. Sunter et al (1991) Actions of the four isomers of 1-aminocyclopentane-1,3-dicarboxylate (ACPD) in the hemisected spinal cord of the neonatal rat. Br.J.Pharmacol. 104 337P.
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    Keywords: cis-ACPD, Ligand-gated Ion Channels, Potent NMDA Agonist, ACPD, Tocris Bioscience
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