ACEA | Cannabinoid Receptors | Potent, Highly Selective CB1 Agonist | Arachidonyl-2¢-chloroethylamide

Category:

7TM Receptors

Cannabinoid Receptors

CB1 Receptors

Cat.No.

Product Name

1319

ACEA

Alternative name(s):

Arachidonyl-2¢-chloroethylamide

ACEA C22H36ClNO N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Price and Availability

Click here for full price details of
ACEA

Other Information:

Canadian customers require a CDSA import permit

Chemical Name: N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Biological Activity:

Potent and highly selective CB₁ receptor agonist (K_i = 1.4 nM). Displays > 1400-fold selectivity over CB₂ receptors. Active in vivo.

Technical Data:

M.Wt:	365.99
Formula:	C₂₂H₃₆ClNO
Storage:	Desiccate at -20°C
Solubility:	Soluble in Ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
CAS No:	[220556-69-4]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Hillard et al (1999) Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 289 1427. Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635. Patel et al (2001) Cannabinoid CB₁ receptor agonists produce cerebellar dysfunction in mice. 2001 Symposium on the Cannabinoids, International Cannabinoid Research Society.

View related products by Pharmacological Action or by Research Area

Keywords: ACEA, Cannabinoid Receptors, Potent, Highly Selective CB1 Agonist, Arachidonyl-2¢-chloroethylamide, Tocris Bioscience

Literature in this Area

Scientific Reviews

Cannabinoid Receptors
Request Copy | Download PDF

Featured New Product

Highly selective CB₂ agonist

2764 Gp 1a

Highly selective CB₂ receptor agonist; K_i values are 0.037 and 363 nM for CB₂ and CB₁ receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.

View all Featured New Products

New Products in this Area

	2797	O-1602
	Potent GPR55 receptor agonist
	2680	O-2545 hydrochloride
	High affinity, water-soluble CB₁/CB₂ agonist
	2836	Arachidonyl serotonin
	Dual FAAH/TRPV1 blocker
	2764	GP 1a
	Highly selective CB₂ agonist
	2678	GP 2a
	Selective CB₂ agonist
	2663	CB 65
	High affinity, selective CB₂ agonist
	2288	O-1918
	Silent antagonist for putative abnormal-CBD receptor
	2434	L-759,656
	Highly selective CB₂ agonist
	2231	Anti-CB₂
	Antibody recognising CB₂ receptors

for new product e-alerts

User ID
Password