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Category:
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Cellular Processes and Components Signal TransductionCalcium SignallingCalcium Binding Protein Modulators
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Cat.No.
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Product Name
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0378 |
A-7 hydrochloride
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Chemical Name:
N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide
hydrochloride |
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Biological Activity:
Potent calmodulin antagonist (inhibits calmodulin-activated PDE
activity with an IC50 of 3 μM)
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin
antagonists. Methods Enzymol. 102 185. Itoh and Hidaka (1984)
Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent
cyclic nucleotide phosphodiesterase. J.Biochem. 96 1721.
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View related products by Pharmacological Action
or by Research Area
Keywords: A-7 Hydrochloride, Signal Transduction, Calmodulin Antagonist, Tocris Bioscience
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Literature in this Area Scientific Reviews
Mechanisms for Manipulating Intracellular Calcium Buffering Download PDF Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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