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Category: EnzymesarrowKinasesarrowBroad Spectrum Protein Kinase Inhibitors
Cat.No. Product Name
0366 A-3 hydrochloride
Price and Availability

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A-3 hydrochloride
Chemical Name: N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

Biological Activity:

Protein kinase inhibitor. Ki values are 4.3, 3.8, 7, 47, 80 and 5.1 μM for PKA, PKG, MLCK, PKC, casein kinase I and casein kinase II respectively.

Technical Data:

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M.Wt: 321.22
Formula: C12H13ClN2O2S.HCl
Storage: Store at RT
Solubility: Soluble to 100 mM in Water

Resources:

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    • Certificate of Analysis / MSDS:

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    References:

    Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 102 185. Hidaka and Hagiwara (1987) Pharmacology of the isoquinolinesulfonamide protein kinase C inhibitors. TIPS 8 162. Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Ann.Rev.Pharmacol.Toxicol. 32 377.
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    Keywords: A-3 Hydrochloride, Kinases, Protein Kinase Inhibitor, A3 Hydrochloride, Tocris Bioscience
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