R&D Systems Inc. Tocris Bioscience Boston Biochem

Prostanoid Receptors

More Information »Prostanoid receptors are activated by the endogenous ligands prostaglandin (PG) D2, PGE2, PGF2α, PGH2, prostacyclin (PGI2) and thromboxane A2. Cyclooxygenase (COX) converts arachidonic acid to PGH2, from which the other prostaglandins are synthesized.

Prostanoid Receptor Products

Product Name / Activity
1442 BMY 45778
Non-prostanoid prostacyclin IP receptor partial agonist
2295 (±)-Cloprostenol sodium salt
Water-soluble PGF2α analog and potent FP receptor agonist
4027 16,16-Dimethyl Prostaglandin E2
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
2989 Epoprostenol
Endogenous IP receptor agonist
4542 (+)-Fluprostenol
High affinity FP prostaglandin receptor agonist
2038 Iloprost
Prostacyclin (PGI2) analog
4757 Latanoprost
FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors
2297 Misoprostol
Cytoprotective PGE1 analog
3351 NS 304
Selective prostacyclin IP1 receptor agonist
2296 Prostaglandin E2
Major endogenous prostanoid
4214 Prostaglandin F2α
Naturally-occurring prostanoid; potent vasoconstrictor
3049 Sulprostone
EP3 and EP1 receptor agonist
4069 TCS 2510
Selective EP4 agonist
4218 Travaprost
Potent and selective FP prostaglandin receptor agonist
1932 U 46619
Potent, stable thromboxane A2 (TP) receptor agonist
Product Name / Activity
3025 AA 2414
Thromboxane A2 (TP) receptor antagonist
0671 AH 6809
EP1 and EP2 receptor antagonist
2732 BAY-u 3405
Dual TP/DP2 (CRTH2) receptor antagonist
4668 GW 627368
Selective EP4 receptor competitive antagonist
0836 ICI 185,282
Potent thromboxane receptor antagonist
0837 ICI 192,605
Potent thromboxane A2/TP receptor antagonist
2514 L-161,982
Selective EP4 receptor antagonist
1698 L-655,240
Potent, selective thromboxane A2/prostaglandin endoperoxide antagonist
1949 L-670,596
Potent, selective thromboxane A2/prostaglandin endoperoxide antagonist
3342 L-798,106
Potent and highly selective EP3 antagonist
3565 ONO AE3 208
High affinity and selective EP4 antagonist
4818 PF 04418948
Potent and selective EP2 receptor antagonist
1206 SC 19220
Selective EP1 receptor antagonist
3758 SC 51089
Selective EP1 receptor antagonist
2791 SC 51322
Potent EP1 receptor antagonist
5052 TG 4-155
High affinity and selective EP2 receptor antagonist
Product Name / Activity
1620 Alprostadil
Prostaglandin. Vasodilator and antiplatelet agent in vivo
2756 Arachidonic acid (in Tocrisolve™100)
Endogenous free fatty acid (in water-soluble emulsion)
1510 Ozagrel hydrochloride
Selective thromboxane A2 synthetase inhibitor
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