R&D Systems Inc. Tocris Bioscience Boston Biochem

Purinergic (P2Y) Receptors

More Information »P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine nucleotides. To date, eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11-14) as well as the non-mammalian p2y3, p2y8 and p2y receptors.

Purinergic (P2Y) Receptor Products

Agonists
Cat.No.
Product Name / Activity
3245 ATP disodium salt
P2 agonist
4080 ATPγS tetralithium salt
P2 agonist; ATP (Cat. No. 3245) analog
3312 BzATP triethylammonium salt
P2Y1 partial agonist. Also P2X7 agonist and P2X1 partial agonist
3209 α,β-Methyleneadenosine 5'-triphosphate trisodium salt
P2 agonist
1624 2-Methylthioadenosine diphosphate trisodium salt
Potent agonist for P2Y1, P2Y12 and P2Y13
1062 2-Methylthioadenosine triphosphate tetrasodium salt
P2 agonist
2157 MRS 2365
Highly potent and selective P2Y1 agonist
2915 MRS 2690
Potent P2Y14 agonist
2502 MRS 2693 trisodium salt
Selective P2Y6 agonist
3884 MRS 2768 tetrasodium salt
Selective P2Y2 agonist
4260 MRS 2957 triethylammonium salt
Potent and selective P2Y6 agonist
4261 MRS 4062 triethylammonium salt
Selective P2Y4 receptor agonist
3892 NF 546
Selective P2Y11 agonist
4376 5-OMe-UDP trisodium salt
Potent P2Y6 agonist
2715 PSB 0474
Potent and selective P2Y6 agonist
4333 PSB 1114
Potent, selective P2Y2 agonist
3280 2-ThioUTP tetrasodium salt
Potent and selective P2Y2 agonist
3279 UTPγS trisodium salt
Selective P2Y2/4 agonist
Antagonists
Cat.No.
Product Name / Activity
3321 AR-C 66096 tetrasodium salt
Potent and selective P2Y12 antagonist
1820 (+)-Clopidogrel hydrogen sulfate
Selective P2Y12 antagonist
2490 (±)-Clopidogrel hydrochloride
Selective P2Y12 antagonist
0900 MRS 2179 tetrasodium salt
Selective P2Y1 antagonist
2402 MRS 2211
Competitive P2Y13 antagonist
2158 MRS 2279
Selective, high affinity P2Y1 antagonist
2159 MRS 2500 tetraammonium salt
Extremely potent and selective P2Y1 antagonist
2146 MRS 2578
Selective P2Y6 antagonist
2450 NF 157
Selective P2Y11/P2X1 antagonist
3830 NF 340
Selective P2Y11 antagonist
0625 PPADS tetrasodium salt
P2 antagonist
3983 PSB 0739
Highly potent P2Y12 receptor antagonist
1472 Suramin hexasodium salt
Non-selective P2 antagonist
3931 Ticlopidine hydrochloride
Selective P2Y12 antagonist
Other
Cat.No.
Product Name / Activity
5157 DMNPE-caged ATP diammonium salt
Caged ATP
1682 PIT
P2Y ligand; displays mixed antagonism/potentiation
3111 UDP disodium salt
Endogenous ligand; competitive antagonist at P2Y14 receptors
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