R&D Systems Inc. Tocris Bioscience Boston Biochem

Toll-like Receptor Signaling Pathway

Pathway Key Download PDF

The toll-like receptors (TLRs) act in response to molecular patterns found in microbes such as bacteria and viruses that pose a biological threat. The signaling pathway leads to the activation of innate and acquired immunity along with an inflammatory response and the upregulation of cytokines.

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Signaling Pathway Key
Stimulates
Stimulates
Multistep Upregulation
Multistep Upregulation
Multistep Activation
Multistep Activation
Translocates
Translocates
Kinase
Kinase
Transcription Factor
Transcription Factor
Enzyme-linked Receptor
Enzyme-linked Receptor
Other Enzyme
Other Enzyme
Other Protein
Other Protein
Endosome
Endosome