R&D Systems Inc. Tocris Bioscience Boston Biochem

Notch Signaling Pathway

Pathway Key Download PDF

The Notch signaling pathway is important in the regulation of cell fate specification, proliferation and death, for neuronal, cardiac and endocrine systems, and most particularly in stem cells. This determines the biological orientation of cells throughout development, allocating different cell types within a tissue.

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Signaling Pathway Key
Stimulates
Stimulates
Inhibits
Inhibits
Upregulation
Upregulates
Translocates
Translocates
Other Protein
Other Protein
Transcription Factor
Transcription Factor
Other Enzyme
Other Enzyme
Transmembrane Protein
Transmembrane Protein