R&D Systems Inc. Tocris Bioscience Boston Biochem

Insulin Signaling Pathway

Pathway Key Download PDF

Signaling through the insulin pathway is very important for the regulation of glucose homeostasis. The hormone insulin is produced in response to nutrients within the blood and leads to the downstream uptake of glucose and synthesis of glycogen. Decreases in insulin receptor signaling may lead to insulin resistance, which can contribute towards the development of Type 2 diabetes.

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Signaling Pathway Key
Stimulates
Stimulates
Inhibits
Inhibits
Multistep Activation
Multistep Activation
Multistep Upregulation
Multistep Upregulation
Translocates
Translocates
Kinase
Kinase
Transcription Factor
Transcription Factor
Enzyme-linked Receptor
Enzyme-linked Receptor
Other Enzyme
Other Enzyme
Other Protein
Other Protein
Proapoptotic
Proapoptotic
Phosphatase
Phosphatase
Transporter
Transporter