R&D Systems Inc. Tocris Bioscience Boston Biochem

Akt Signaling Pathway

Pathway Key Download PDF

The Akt/PI 3-Kinase signaling pathway is involved in fundamental cellular processes including protein synthesis, proliferation and survival. PI 3-kinase is activated following ligand binding to a range of receptors which activates Akt downstream, phosphorylating a wide range of substrates and initiating cellular events.

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Signaling Pathway Key
Stimulates
Stimulates
Inhibits
Inhibits
Multistep Activation
Multistep Activation
Translocates
Translocates
Kinase
Kinase
Transcription Factor
Transcription Factor
Enzyme-linked Receptor
Enzyme-linked Receptor
Other Enzyme
Other Enzyme
Other Protein
Other Protein
Phosphatase
Phosphatase
Proapoptotic
Proapoptotic
Prosurvival
Prosurvival
7-TM Receptor
7-TM Receptor