R&D Systems Inc. Tocris Bioscience Boston Biochem

Life Science Posters

A range of posters authored by leading experts

Authored by leading experts in the field, and summarizing key areas of research, the following range of life science posters provide a colorful and informative source of information. We invite you to request your copy today.

Request 7-TM poster


Seven Transmembrane Receptor Signaling

Terry Kenakin, GlaxoSmithKline Research and Development
Robert Lefkowitz and Jonathan Violin, Duke University Medical Center
Michel Bouvier and Geneviève Oligny-Longpré, Université de Montréal

Seven-transmembrane (7-TM)-receptors are now recognized as complex processors of information that can bind to molecules and cytosolic interactants on the cell membrane. The 7-TM poster highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy.

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Request Alzheimer's poster


The Neurobiology of Alzheimer's Disease

Alan M. Palmer, MS Therapeutics Ltd.

Alzheimer's disease is the most common form of dementia, affecting approximately 26.6 million people worldwide. This poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease.

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Request Angiogenesis poster


Tumor- and Stromal Cell-Derived Pathways as Targets for Anti-Angiogenic Therapy

Napoleone Ferrara and Yongping Crawford, Genentech

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

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Request asthma poster


New Therapies, Challenges, and Breakthroughs in Asthma

Peter J. Barnes, Imperial College London

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.

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Request Autophagy poster


Autophagy: Mechanisms and Function

Patricia Boya, CSIC
Patrice Codogno, University Paris-Descartes

Autophagy is a cellular process used by cells for degradation and recycling. This poster summarizes the molecular machinery, physiology and pathology of autophagy.

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Request Cardiovascular poster


Regulation of Vascular Reactivity by G-protein-coupled Receptors

Janet J. Maguire and Anthony P. Davenport, University of Cambridge

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Since going to print, the authors of this poster have notified us of an improvement they wish to make: under the Gq/11 heading, M2 should be amended to M3.

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Request Cell Cycle Kinases poster

Cell Cycle Kinases

Checkpoint Kinases and the DNA Damage Response

Michelle D. Garrett and Ian Collins, Institute of Cancer Research

Checkpoint kinases are a group of enzymes which regulate the progression of a cell through the cell cycle. This poster summarizes the response of the checkpoint kinase signaling network to DNA damage, including activation of DNA repair, cell-cycle arrest, senescence and apoptosis. It also highlights the different types of DNA damage that can occur and some of the treatment methods that are utilized in cancer.

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Request Depression poster


Antidepressants - Current and Future Targets

Phil Skolnich, New York University
Piotr Popik, Polish Academy of Sciences
Ramon Trullas, Institut d'Investigacions Biomediques de Barcelona

Major depressive disorder (MDD) effects approximately 15% of the population in developed countries. This poster provides an overview of the current and future targets for the treatment of MDD.

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Request Gut Hormones poster

Gut Hormones

Gut Hormones and the Regulation of Appetite

Victoria J. Taylor, Preeti H. Jethwa, Caroline J. Small and Stephen R. Bloom, Imperial College London

The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.

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Reserve Learning and Memory poster

Learning and Memory

Neurotransmitters of Synaptic Plasticity, Learning and Memory in the Perirhinal Cortex

E. Clea Warburton and Zafar I. Bashir, University of Bristol

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

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Request Neuroprotection poster


Calcium Imbalance and Neuroprotective Targets in Cerebral Ischemia and Brain Injury

Elaine F. Besancon, Suzhen Guo, Josephine Lok and Eng H. Lo, Harvard Medical School
Michael Tymianshi, University of Toronto

After cerebral ischemia and brain injury, a wide spectrum of pathophysiological mechanisms are activated. This poster summarizes the key receptors, transporters and intracellular signals that might reveal a neuroprotective target for stroke, trauma and neurodegeneration.

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Request p53 poster


Strategies to Reactivate the p53 Tumor Suppressor Response

Christopher J. Brown, Chit F. Cheok, David P. Lane and Chandra S. Verma, A*STAR

p53 is a key transcriptional regulator that is found to be frequently mutated and inactivated in tumors. This poster summarizes the main strategies that may be utilized to reactivate p53 including several small molecules and peptides which act to stabilize p53 and rescue wild-type activity.

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Reserve Pain poster


Excitatory and Inhibitory Mechanisms Underlying Peripheral Sensitization

Grant D. Nicol and Michael R. Vasko, Indiana University

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

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Request Parkinson's disease poster


Parkinson's Disease: Neurobiology and Therapeutic Strategies

Anthony H.V. Schapira, University College London

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.

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Request Programmed Cell Death poster

Programmed Cell Death

Apoptosis, Necroptosis and Cell Survival

Bram van Raam, Universiteit Gent
Guy Salvesen, Sanford-Burnham Medical Research Institute

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

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Request schizophrenia poster


Schizophrenia: Emerging Targets and Therapeutic Strategies

Jeffery Lieberman, Jacob Ballons, Nancy Bivens, Zachary Freyberg, Ragy Girgis,
Caline Karam, Jose Lizardi-Ortiz, Sander Markx and Jonathan Javitch,
Columbia University College of Physicians and Surgeons

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster highlights the targets and pathways representing the most promising strategies to pursue for novel drug development.

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