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Ro 04-5595 hydrochloride

Cat. No. 2005

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Chemical Name: 1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinol hydrochloride

Biological Activity

Selective antagonist for NR2B-containing NMDA receptors (K_i = 31 nM).

Technical Data

M.Wt:

368.3

Formula:

C₁₉H₂₂ClNO₂.HCl

Solubility:

Soluble to 15 mM in water and to 100 mM in DMSO

Purity:

>98 %

Storage:

Desiccate at +4°C

CAS No:

194089-07-1

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Mutel et al (1998) In vitro binding properties in rat brain of [³H] Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits. J.Neurochem. 70 214.

If you know of a relevant citation for this product please let us know.

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Keywords: Ro 04-5595 hydrochloride, supplier, Selective, NR2B, antagonists, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Ro04-5595, hydrochloride

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