Ro 04-5595 hydrochloride

Cat. No. 2005

Ro 04-5595 hydrochloride C19H22ClNO2.HCl [64047-73-0]

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Chemical Name: 1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinol hydrochloride

Biological Activity

Selective antagonist for NR2B-containing NMDA receptors (Ki = 31 nM).

Technical Data

Soluble to 15 mM in water and to 100 mM in DMSO
>98 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Mutel et al (1998) In vitro binding properties in rat brain of [3H] Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits. J.Neurochem. 70 214.

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Keywords: Ro 04-5595 hydrochloride, supplier, Selective, NR2B, antagonists, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Ro04-5595, hydrochloride, NMDA Receptor Antagonists

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