Home » Pharmacology » Ion Channels » Transient Receptor Potential Channels » TRPV » 6-Iodonordihydrocapsaicin

6-Iodonordihydrocapsaicin

Cat. No. 1975

Price and Availability

For 6-Iodonordihydrocapsaicin pricing & availability please select your country from the drop down menu:
Submit

By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Potent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC₅₀ = 10 nM). Inhibits capsaicin-induced [Ca²⁺]_i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.

Technical Data

M.Wt:

419.3

Formula:

C₁₇H₂₆INO₃

Solubility:

Soluble to 50 mM in ethanol and to 100 mM in DMSO

Purity:

>99 %

Storage:

Store at RT

CAS No:

859171-97-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Select another batch:

Safety Data Sheet: View Safety Data Sheet

References

Appendino et al (2003) Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. Br.J.Pharmacol. 139 1417. PMID: 12922928.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Transient Receptor Potential Channels

TRPV

Keywords: 6-Iodonordihydrocapsaicin, supplier, Potent, competitive, vanilloids, receptors, antagonists, VR1, TRPV, Channels, Transient, Receptor, Potential