Cat. No. 1975
Biological ActivityPotent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC50 = 10 nM). Inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Appendino et al (2003) Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. Br.J.Pharmacol. 139 1417. PMID: 12922928.
If you know of a relevant citation for this product please let us know.
Keywords: 6-Iodonordihydrocapsaicin, supplier, Potent, competitive, vanilloids, receptors, antagonists, VR1, TRPV, Channels, Transient, Receptor, Potential
Find multiple products by catalog number
New Products in this Area
Selective TRPM3 agonistMRS 1477
TRPV1 positive allosteric modulatorMK6-83
TRPML channel activatorTC-I 2014
Potent TRPM8 antagonistASP 7663
Selective TRPA1 activatorRQ 00203078
Potent and selective TRPM8 antagonist; orally active
September 7 - 9, 2015