R&D Systems Inc. Tocris Bioscience Boston Biochem

6-Iodonordihydrocapsaicin

Cat. No. 1975

6-Iodonordihydrocapsaicin C17H26INO3 [859171-97-4]

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Biological Activity

Potent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC50 = 10 nM). Inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.

Technical Data

M.Wt:
419.3
Formula:
C17H26INO3
Solubility:
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
859171-97-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Appendino et al (2003) Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. Br.J.Pharmacol. 139 1417. PMID: 12922928.

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View Related Products by Target

Keywords: 6-Iodonordihydrocapsaicin, supplier, Potent, competitive, vanilloids, receptors, antagonists, VR1, TRPV, Channels, Transient, Receptor, Potential

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