Pharmacology
All Targets
7-TM Receptors
Ion Channels
Nuclear Receptors
Enzyme-Linked Receptors
Transporters
Enzymes
Other Pharmacology
Cellular Processes
Angiogenesis
Apoptosis
Cell Cycle
Cell Metabolism
Cytoskeleton & Motor Proteins
ECM & Adhesion Molecules
Signal Transduction
Stem Cells
Product Type
All Products
New Products
Small Molecules
Peptides
Antibodies
Jena Bioscience
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular Disease
Endocrinology
Immunology
Metabolic Disease
Neurological Disease
Pain & Inflammation
Respiratory Disease
Home »
Pharmacology » 7-TM Receptors » 5-HT Receptors » 5-HT1 Receptors » 5-HT1D Receptors » L-703,664 succinate
L-703,664 succinateCat No. 2640 |
Price and Availability |
|
Chemical Name: N,N-Dimethyl-5-[(5-methyl-1,1-dioxodo-1,2,5-thiadiazoli din-2-yl)methyl]-1H-indole-3-ethanamine succinate |
|
Biological Activity
5-HT1D receptor agonist that displays selectivity over other 5-HT receptor subtypes (pIC50 values are 7.2, 6.1, < 5.0 and < 5.0 for 5-HT1D, 5-HT1A, 5-HT2A and 5-HT3 respectively) and other receptors (pIC50 < 5.0 for adenosine, adrenergic, excitatory amino acids, dopamine, histamine, muscarinic, nicotinic and opiate receptors).Licensing Information
Sold with the permission of Merck, Sharpe and Dohme Ltd.Technical Data
M.Wt:454.54
Formula:C16H24N4O2S.C4H6O4
Solubility:Soluble to 50 mM in water and to 100 mM in DMSO
Purity: >99 %
Storage:Store at +4°C
CAS No:[144776-01-2]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Castro et al (1994) Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin-2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor. J.Med.Chem. 37 3023.If you know of a useful citation for this product please let us know.
Keywords: L-703,664 succinate, Selective, 5-HT1D, receptor, agonists, Serotonin, Receptors
Buy Now / Print Quote
Find multiple products by catalog number
New Products in this Area
NAD 299
Selective, high affinity 5-HT1A receptor antagonist
Donitriptan hydrochloride5-HT1B/1D agonist
CP 135807Selective 5-HT1D agonist
Eletriptan hydrobromideOrally active, selective 5-HT1B/1D agonist
Sign-up for new product e-alerts
Special Offer
25% discount* on selected Tocris products:
To view more special offers....



