Cat. No. 1903
Biological ActivityPeptide derived from the heparin-binding domain in the B1 chain of laminin. Binds to heparin, promotes cell adhesion, and inhibits the migration towards, and adhesion of metastatic fibrosarcoma cells to laminin.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Charonis et al (1988) A novel synthetic peptide from the B1 chanin of laminin with heparin-binding and cell adhesion-promoting activities. J.Cell Biol. 107 1253. PMID: 3417782.
Skubitz et al (1990) Definition of a sequence, RYVVLPR, within laminin peptide F-9 that mediates metastatic fibrosarcoma cell adhesion and spreading. Cancer Res. 50 7612. PMID: 2253210.
Schuger et al (1996) Laminin and heparan sulfate proteoglycan mediate epithelial cell polarization in organotypic cultures of embryonic lung cells: evidence implicating involvement of the inner globular region of laminin β 1 chain and the heparan sulfate groups of heparan sulfate proteoglycan. Dev.Biol. 179 264. PMID: 8873769.
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Keywords: Peptide F9, supplier, inhibitors, laminin-mediated, cell, adhesion, migration, Adhesion, Molecules, heparin, PeptideF9
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June 21, 2013