R&D Systems Inc. Tocris Bioscience Boston Biochem

Mastoparan X

Cat. No. 1896

Mastoparan X Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2

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Biological Activity

Amphiphilic G protein activator peptide that binds to Gi and Go. Also binds with high affinity to calmodulin (Kd ~ 0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 4.4 mM).

Technical Data

M.Wt:
1555.98
Formula:
C73H126N20O15S
Sequence:
INWKGIAAMAKKLL

(Modifications: Leu-14 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
72093-22-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176. PMID: 2117607.

Sukumar and Higashijima (1992) G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide. J.Biol.Chem. 267 21421. PMID: 1400455.

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799. PMID: 10329678.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Mastoparan X, supplier, G, protein, activators, peptide, Gi, Go, Heterotrimeric, MastoparanX

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