Home » Cellular Processes » Apoptosis » Apoptosis Inducers » Oxaliplatin

Oxaliplatin

Cat No. 2623

Price and Availability

For Oxaliplatin pricing & availability please select your country from the drop down menu:
Submit

Alternative Name: Eloxatin

Chemical Name: Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)

Biological Activity

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance.

Technical Data

M.Wt:

397.29

Formula:

C₈H₁₄N₂O₄Pt

Solubility:

Soluble to 10 mM in water and to 50 mM in DMSO

Purity:

>99 %

Storage:

Store at +4°C

CAS No:

[61825-94-3]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References

Culy et al (2000) Oxaliplatin. A review of its pharmacological properties and clinical efficacy in metastatic colorectal cancer and its potential in other malignancies. Drugs 60 895. Raymond et al (2002) Cellular and molecular pharmacology of oxaliplatin. Mol.Cancer Ther. 1 227. Mani et al (2002) Oxaliplatin: a review of evolving concepts. Cancer Invest. 20 246.

If you know of a useful citation for this product please let us know.