R&D Systems Inc. Tocris Bioscience Boston Biochem

pp60 c-src (521-533) (phosphorylated)

Cat. No. 1923

pp60 c-src (521-533) (phosphorylated) Thr-Ser-Thr-Glu-Pro-Gln-pTyr-Gln-Pro-Gly-Glu-Asn-Leu

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Biological Activity

Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.

Technical Data

M.Wt:
1543.5
Formula:
C62H95N16O28P
Sequence:
TSTEPQYQPGENL

(Modifications: Tyr-7 = pTyr)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
149299-77-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Roussel et al (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60c-src. Proc.Natl.Acad.Sci.U.S.A. 88 10696. PMID: 1720546.

Harder et al (1994) Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 298 395. PMID: 8135747.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: pp60 c-src (521-533) (phosphorylated), supplier, inhibitors, tyrosine, kinase, activity, pp60c-src, pp60v-src, Src, Kinases

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