Ro 26-4550 trifluoroacetate

Cat. No. 1794

Ro 26-4550 trifluoroacetate C26H30N4O3.CF3CO2H [1217448-66-2]

Price and Availability

For Ro 26-4550 trifluoroacetate pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-[[(3R)-1-(Aminoiminomethyl)-3-piperidinyl]acetyl]-4-(phenylethynyl)-L-phenylalanine methyl ester trifluoroacetate

Biological Activity

Competitive reversible inhibitor of interleukin-2 (IL-2) binding to its receptor (IC50 = 3 μM for inhibition of IL-2 interaction with IL-2R α-subunit). Appears to compete with IL-2Rα for its binding site on IL-2.

Technical Data

M.Wt:
560.57
Formula:
C26H30N4O3.CF3CO2H
Solubility:
Soluble to 50 mM in DMSO and to 5 mM in ethanol
Purity:
>98 %
Storage:
Desiccate at +4°C
CAS No:
1217448-66-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Tilley et al (1997) Identification of a small molecule inhibitor of the IL-2/IL-2Rα receptor interaction which binds to IL-2. J.Am.Chem.Soc. 119 7589.

Braisted et al (2003) Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J.Am.Chem.Soc. 125 3714. PMID: 12656598.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Ro 26-4550 trifluoroacetate, supplier, Competitive, inhibitors, IL-2/, IL-2Ralpha, interaction, IL, Receptors, Interleukins, Cytokines, Ro26-4550, Tocris Bioscience, Cytokine Receptors

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Immunology Guide

Immunology Product Listing

Highlights over 190 products for immunology research. Request copy or view PDF today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

A summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

divider line

New Products in this Area

6877002

CD40-TRAF6 interaction inhibitor

Sign-up for new product e-alerts
divider line

AAI 2016

Win a $1,000 travel grant

AAI Travel Grant

Bio-Techne is offering 10 travel grants of $1,000 for AAI 2016.