R&D Systems Inc. Tocris Bioscience Boston Biochem

Bax inhibitor peptide V5

Cat. No. 1785

Bax inhibitor peptide V5 Val-Pro-Met-Leu-Lys

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Biological Activity

Cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro. Negative control (Cat. No. 1787) available.

Licensing Information

Sold under license

Technical Data

M.Wt:
586.79
Formula:
C27H50N6O6S
Sequence:
VPMLK
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
579492-81-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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References

Yoshida et al (2004) Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 321 961. PMID: 15358121.

Sawatzky et al (2006) The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 168 33. PMID: 16400007.

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View Related Products by Target

Keywords: Bax inhibitor peptide V5, supplier, inhibitors, Bax-mediated, apoptosis, Bcl-XL, Mcl-1, Bcl-2, Family, Bax, inhibitor, peptideV5

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