Bax inhibitor peptide V5
Cat. No. 1785
Biological ActivityCell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro. Negative control (Cat. No. 1787) available.
Licensing InformationSold under license
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Yoshida et al (2004) Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 321 961. PMID: 15358121.
Sawatzky et al (2006) The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 168 33. PMID: 16400007.
If you know of a relevant citation for this product please let us know.
Keywords: Bax inhibitor peptide V5, supplier, inhibitors, Bax-mediated, apoptosis, Bcl-XL, Mcl-1, Bcl-2, Family, Bax, inhibitor, peptideV5
Find multiple products by catalog number
New Products in this Area
Dimeric Smac mimetic; potent IAP inhibitorFerrostatin 1
Selective inhibitor of erastin induced ferroptosisCFM 4
CARP-1 mimetic; proapoptoticNecrosulfonamide
Necroptosis inhibitorFK 866 hydrochloride
Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.