Cat. No. 2863
Alternative Name: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride
Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzen
Biological ActivitySelective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Titiler et al (1987) Selectivity of serotonergic drugs for multiple brain serotonin receptors. Biochem.Pharmacol. 36 3265. PMID: 3663239.
McKenna et al (1989) Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J.Neurosci. 10 3482.
Arvanov et al (1999) A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex. Eur.J.Neurosci. 11 2917. PMID: 10457188.
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Keywords: DOB hydrochloride, supplier, Selective, 5-HT2, agonists, Non-Selective, Serotonin, Receptors