R&D Systems Inc. Tocris Bioscience Boston Biochem

DOB hydrochloride

Cat. No. 2863

DOB hydrochloride C11H16BrNO2.HCl [29705-96-2]

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Alternative Name: 2,5-Dimethoxy-4-bromoamphetamine hydrochloride

Chemical Name: 4-Bromo-2,5-dimethoxy-α-methylbenzeneethanamine hydrochloride

Biological Activity

Selective 5-HT2 receptor agonist (Ki values are 0.44, 59, 69, 831 and 3700 nM for 5-HT2H, 5-HT2L, 5-HT2C, 5-HT1B and 5-HT1A receptors respectively). Hallucinogenic.

Technical Data

M.Wt:
310.62
Formula:
C11H16BrNO2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
29705-96-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Titiler et al (1987) Selectivity of serotonergic drugs for multiple brain serotonin receptors. Biochem.Pharmacol. 36 3265. PMID: 3663239.

McKenna et al (1989) Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J.Neurosci. 10 3482.

Arvanov et al (1999) A pre- and postsynaptic modulatory action of 5-HT and the 5-HT2A,2C receptor agonist DOB on NMDA-evoked responses in the rat medial prefrontal cortex. Eur.J.Neurosci. 11 2917. PMID: 10457188.

If you know of a relevant citation for this product please let us know.

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Keywords: DOB hydrochloride, supplier, Selective, 5-HT2, agonists, Non-Selective, Serotonin, Receptors

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