Cat. No. 2970
Chemical Name: (7α,17α)-17-Hydroxy-3-oxo-7-propylpre
Biological ActivityMineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261.
Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737. PMID: 2333987.
Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563. PMID: 17569793.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: RU 26752, supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752
Find multiple products by catalog number
New Products in this Area
High affinity aryl hydrogen receptor (AhR) agonistML 179
Selective liver receptor homolog 1 (LRH1) inverse agonistAC 186
Potent and selective ERβ agonist; neuroprotectiveIsotretinoin
Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiationBTC
Selective estrogen receptor modulator (SERM)
September 5 - 8, 2015