R&D Systems Inc. Tocris Bioscience Boston Biochem

RU 26752

Cat. No. 2970

RU 26752 C25H36O3 [76676-33-0]

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Chemical Name: (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid γ-lactone

Biological Activity

Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.

Technical Data

M.Wt:
384.55
Formula:
C25H36O3
Solubility:
Soluble to 25 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
76676-33-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261.

Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737. PMID: 2333987.

Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563. PMID: 17569793.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: RU 26752, supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752

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